Extreme Elevation of Alkaline Phosphatase in a Pregnancy Complicated by Gestational Diabetes and Infant with Neonatal Alloimmune Thrombocytopenia
نویسندگان
چکیده
There have been few case reports of isolated elevation of alkaline phosphatase beyond the normal physiologic amount with subsequent return to baseline after delivery. Here we present a similar case of extreme elevation of alkaline phosphatase in a pregnancy complicated by gestational diabetes and subsequently by neonatal alloimmune thrombocytopenia (NAIT).
منابع مشابه
Profiling Glycated Hemoglobin Level, Lactate Dehydrogenase and Alkaline Phosphatase Activity in Gestational Diabetes Mellitus Obese Women and Compare Them with Each Other
Background and Aims: The aim of this study was profiling glycated hemoglobin (HbA1c) level, lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) activity in obese women with gestational diabetes mellitus (GDM) and evaluating the correlation between them. Materials and Methods: Sample size was 90 subjects admitted to the clinical laboratory, who were divided into three groups, in each g...
متن کاملشیوع ترومبوسیتوپنی در بارداری و عوامل مرتبط با آن
Background and purpose: After anemia thrombocytopenia is the most common disorder in pregnancy which is encountered in 10% of pregnancies. Thrombocytopenia in pregnant women may lead to maternal and neonatal morbidity. This condition could involve some complications in pregnancy, so diagnosing its causes is important for treatment. This study was performed to determine the incidence, causes and...
متن کاملFetal-maternal complications and their association with gestational thrombocytopenia.
OBJECTIVES Thrombocytopenia is defined as a platelet count of < 150 × 10⁹/L. It is a common hematologic abnormality during pregnancy. Evaluation and treatment of gestational thrombocytopenia can be both, expensive and invasive, and may result in an adverse outcome. The aim of our study was to investigate the incidence of perinatal complications in pregnancies complicated with gestational thromb...
متن کاملNeonatal alloimmune thrombocytopenia complicated by maternal autoimmune thrombocytopenia.
Neonatal alloimmune thrombocytopenia should be suspected in any thrombocytopenic infant born to a healthy non-thrombocytopenic mother. Nevertheless, the condition occurs in only 1 or 2/10 000 births.' More often transient neonatal immune thrombocytopenia results from maternal idiopathic thrombocytopenic purpura. We report the coexistence of alloimmunisation and autoimmunisation against platelet...
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Background Treatment for neonatal alloimmune thrombocytopenia (NAIT) primarily involves maternal administration of intravenous immunoglobulin (IVIG) therapy and prednisone according to protocols based on risk stratification. While IVIG is generally well tolerated, hematologic side effects are a potential complication. Case We present the successful management of a rare complication of materna...
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عنوان ژورنال:
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016